The amount of calls that come to the helpdesks around the world, that are caused by people not knowing anything about Word/Excel is astounding.
In the old days of office applications you needed to know all the keystrokes and macros and control codes. Remember the keyboard overlays you could buy for each word processor/spreadsheet? You basically had to be an expert to be proficient.
Then they went and dumbed it down, adding menus, buttons, giving everyone mice, the power of WYSIWYG. Now every idiot in the office could print out a mispelled sign about keeping the counters clean in 48 point comic sans, print it in landscape and tape it to the microwave.
Microsoft continues to screw stuff up by adding things like 'Reading Mode'. I've seen office staff brought to tears when a document is automatically opened in reading mode by a middle manager who thinks that matches the print layout, and lays into them about how it looks.
These days you unknowingly launch a document in Word for the web and it's in read-only mode because of Sharepoint permissions that aren't clear, so you can't toggle the checkboxes and it takes 3 co-workers to figure out what went wrong.